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Search Results for " glutathione s-transferase "
Targets Recommended: Glutathione Peroxidase GST

35

抑制剂 & 化合物

10

天然产物

10

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T11505 GSTO1-IN-1

Glutathione Peroxidase; GST Metabolism; oxidation-reduction
GSTO1-IN-1 是谷胱甘肽 S-转移酶 omega 1 抑制剂,IC50=31 nM。
T4564 Ethacrynic acid

Edecrin,利尿酸,Etacrynic Acid,Hydromedin

Others; Calcium Channel; NF-κB; GST Membrane transporter/Ion channel; Metabolism; NF-κB; Others; oxidation-reduction
Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂,也是NF-κB 信号传导途径的有效抑制剂,并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道,从而导致气道平滑肌细胞松弛。它是利尿剂,具有抗炎特性,可减轻类维生素 A 诱导的小鼠耳部水肿。
T5097 Ezatiostat

TER199(free base),TLK199

Apoptosis; Glutathione Peroxidase; GST Apoptosis; Metabolism; oxidation-reduction
Ezatiostat (TER199(free base)) 是一种谷胱甘肽的三肽类似物,也是一种选择性的口服活性的谷胱甘肽 S-转移酶 P1-1 (GSTP1) 抑制剂。它通过抑制GSTP1导致 JNK 激活,刺激淋巴细胞生成和骨髓祖细胞增殖,可研究骨髓增生异常综合症。
T22776 Ezatiostat hydrochloride

TLK199 HCl,Ezatiostat盐酸盐,TER199

Glutathione Peroxidase Metabolism
Ezatiostat hydrochloride (TLK199 HCl) 是一种新型谷胱甘肽类似物,可刺激淋巴细胞生成和骨髓祖细胞增殖,可用于治疗血细胞减少症和研究骨髓增生异常综合症。它也是口服活性的选择性谷胱甘肽 S-转移酶 P1-1 抑制剂,通过抑制 GSTP1导致 JNK 激活。
T24807 S-Methylglutathione

Glutathione S-methyl ester,Glutathione ester,S-Methyl glutathione

Glyoxalase Proteases/Proteasome
S-Methylglutathione (S-Methyl glutathione) 是一种 S 取代的谷胱甘肽,是一种转移酶A催化的1-氯-2,4-二硝基苯偶联物的抑制剂,也是一种 XOCl 清除剂。S-Methylglutathione 抑制乙二醛酶 1 (glyoxalase 1) ,诱导水螅触手球形成。
T5862 Ezatiostat TFA

TER199(free base),Ezatiostat TFA (free base),Ezatiostat,TLK199

GST oxidation-reduction
Ezatiostat TFA (TLK199) 是一种具有造血刺激活性的谷胱甘肽 S-转移酶 (GST) P1-1 的脂质体小分子谷胱甘肽类似物抑制剂。
T12189 NBDHEX

Apoptosis; Glutathione Peroxidase; Autophagy Apoptosis; Autophagy; Metabolism
NBDHEX 是一种谷胱甘肽 S-转移酶 P1-1 抑制剂,也是晚期自噬抑制剂。它诱导肿瘤细胞凋亡,通过抑制 GST 的催化活性,避免抑制剂被特异性泵从细胞中排出,以及破坏 GSTP1-1和关键信号传导因子之间的相互作用,从而起到抗癌的作用。
T0153 Oltipraz

吡噻硫酮,NSC 347901,RP 35972

HIF/HIF Prolyl-Hydroxylase; HIV Protease; Reverse Transcriptase; Nrf2; HIF Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; Microbiology/Virology; Proteases/Proteasome
Oltipraz (RP 35972) 是一种 Nrf2的强效激活剂。它时间依赖性地抑制 HIF-1α激活,IC50为 10 μM,浓度 ≥ 10 μM 时完全消除 HIF-1α诱导。
T23929 Cysfluoretin

Cysfluoretin has glutathione S-transferase inhibitory activity.
T26374 (S)-alpha-Fluoromethylhistidine 2 HCl

(S)-alpha-Fluoromethylhistidine 2 HCl is a potent irreversible inhibitor of histidine decarboxylase (HDC) and glutathione S-transferase.
T11504 GSTO-IN-2

Others Others
GSTO-IN-2 is a glutathione S-transferase inhibitor (IC50s: 1.4, 16.3, and 3.6 μM for GSTP1-1, GSTM1, and GSTA2).
T8424 TLK117

TER117

Others Others
TLK117 selective inhibits Glutathione S-transferase P1–1 (GSTP1-1)(Ki of 0.4 μM for GSTP).
T25160 BITC-SG

BITC-SG inhibits human glutathione S-transferase P1-1 by S-thiocarbamoylation.
T27541 Hexylglutathione

NSC 131114,NSC-131114,NSC131114,S-Hexylglutathione

Hexylglutathione, a glutathione-S-transferase inhibitor, is used to study the effects of phase II enzymes and glutathione.
T81136 S-Octylglutathione

S-Octylglutathione 是一种针对谷胱甘肽硫转移酶 (GST) 的竞争性抑制剂。
T39906 LAS17

LAS17

LAS17 is a potent and selective tyrosine-directed irreversible inhibitor for glutathione S-Transferase Pi ( GSTP1 ). LAS17 inhibits GSTP1 activity with an IC 50 of 0.5 μM.
T68464 PABA/NO

PABA/NO is a novel glutathione-S-transferase-p-activated nitric oxide donor, inhibiting proliferation and inducing apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells.
T72328 Cyclopropenone probe 1

Cyclopropenone probe 1 可以通过在催化活性位点共价结合,特异且有效地修饰三阴性乳腺癌驱动因子 GSTP1。
T78800 GST-IN-1

GST-IN-1 (compound 16) 为一种谷胱甘肽 S-转移酶 (GST) 抑制剂,其半抑制浓度 (IC50s) 分别针对sjGST为1.55 μM,针对hGSTM2为2.02 μM。
T70798 Benastatin B

Benastatin B is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; Ki = 3.7 µM for the rat liver enzyme).2 Benastatin B also inhibits the transglycosylase activity of A. baumannii, C. difficile, E. coli, and S. aureus recombinant penicillin-binding proteins (PBPs; IC50s = 16, 53.3, 30.7, and 31.6 µM, respectively).3 It is active against several bacteria, including methicillin-resistant S....
T35979 Benastatin C

Benastatin C is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2It inhibits glutathione S-transferase (GST; IC50= 24 μg/ml for the rat liver enzyme).2Benastatin C also inhibits the esterase activity of isolated porcine pancreatic lipase (IC50= 10 μg/ml). It increases LPS- or concanavalin A-induced blastogenesis of isolated mouse spleen lymphocytes in a concentration-dependent manner. 1.Xu, Z., Schenk, A., and Hertweck, C.Molecul...
T37302 PCTR3

Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutathione S-transferase and to PCTR2 and PCTR3 via peptidases. PCTR3 is found in infected mouse spleens and resolving exudate as well as isolated human spleen and septic plasma. It is also found in both M1 and M2 macrophages differentiated from isolated human monocytes.
T37301 PCTR2

Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutathione S-transferase and to PCTR2 via γ-glutamyl transpeptidase. PCTR2 is found in resolving mouse exudate and in both M1 and M2 macrophages differentiated from isolated human monocytes.
T67975 canfosfamide hydrochloride

Canfosfamide Hydrochloride 是一种改性谷胱甘肽类似物的盐酸盐,具有潜在的抗肿瘤活性。canfofamide 可被谷胱甘肽s -转移酶P1-1选择性激活,转化为与肿瘤细胞DNA 亲核中心形成共价键的烷基化代谢物,从而诱导细胞应激反应和细胞毒性,减少肿瘤增殖。
T75245 Canfosfamide

Canfosfamide (TLK-286) 是一种谷胱甘肽类似物前体药物,由谷胱甘肽 S-转移酶 P1-1 激活,诱导细胞凋亡 (apoptosis)。Canfosfamide 还抑制 DNA 依赖性蛋白激酶 (DNA-PK) 的催化激酶活性。Canfosfamide 在活化后产生一种抗癌烷基化剂和谷胱甘肽衍生物。Canfosfamide 可用于恶性肿瘤的研究。
T35978 Benastatin A

Benastatin A is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2,3It inhibits glutathione S-transferase (GST; Ki= 5 μM for the rat liver enzyme).2Benastatin A is active against several bacteria, including methicillin-resistantS. aureus(MRSA; MIC = 3.12 μg/ml). It induces apoptosis and cell cycle arrest at the G1/G0phase in Colon 26 mouse colon cancer cells when used at concentrations of 20 and 16 μM, respectively.3 1.Xu, Z., Sch...
T69978 Brostallicin HCl

Brostallicin is a synthetic, alpha-bromoacrylic, second-generation minor groove binder (MGB), related to distamycin A, with potential antineoplastic activity. Brostallicin binds to DNA minor groove DNA, after having formed a highly reactive glutathione (GSH)-brostallicin complex in the presence of the enzyme glutathione S-transferase (GST), which is overexpressed in cancer cells; DNA replication and cell division are inhibited, resulting in tumor cell death. Compared to typical MGBs, this agent ...
T37506 MCTR2

MCTR2

Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase then to MCTR2 by γ-glutamyl transferase. MCTR2 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR2 prior to E. coli administration reduces neutrophil infiltration, shor...
T36074 S-NEPC

Cytochrome P450 metabolites of arachidonic acid, such as 11(12)-EpETrE and 14(15)-EpETrE have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EpETrEs to the corresponding DiHETrEs thereby diminishing their activity. Inhibitors of sEH may therefore have clinical utility for treating hypertension and systemic inflammation. S-NEPC is a colorimetric substrate used to measure sEH activity. It also is...
T36170 A1-Phytoprostane-I

A1-Phytoprostane-I

A1-Phytoprostane-I is a cyclopentenone isoprostane produced by the action of reactive oxygen species on α-linolenic acid in plants. There are two A1-phytoprostanes, both having the single ketone group on the ring structure. This isoform results from cyclization between carbons 9 and 13 of linolenic acid, as opposed to carbons 3 and 7 in A1-phytoprostane-II. A1-Phytoprostanes induce the expression of glutathione-S-transferase, increase phytoalexin biosynthesis, and trigger the expression of sever...
T37300 PCTR1

PCTR1

Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by glutathione S-transferase. PCTR1 levels increase during resolution of acute microbial-induced peritonitis in mice. PCTR1 (30 ng, i.p.) administration 12 hours post-infection increases macrophage numbers and activity and shortens the resolution phase of inflammation by 57%. It als...
T74600 Keap1-Nrf2-IN-9

Keap1-Nrf2-IN-9(compound 11)是一种有效Keap1-Nrf2PPI抑制剂,IC50为0.575 µM。该化合物能够提升Nrf2靶基因表达,涉及血红素加氧酶1 (Hmox1)、谷胱甘肽S转移酶P (GstP) 以及谷氨酸-半胱氨酸连接酶的催化(Gclc)与调节(Gclm)亚基。在ARPE19细胞中,Keap1-Nrf2-IN-9展现出无细胞毒活性。
T37507 MCTR3

MCTR3

Maresin conjugates in tissue regeneration 3 (MCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase, then to MCTR2 by γ-glutamyl transferase, and to MCTR3 by dipeptidase. MCTR3 accelerates tissue regeneration in planaria (1 and 100 nM) approximately as potently as MCTR2 and more potently than MCTR1. Pretreatment with MCTR3 pri...
T68581 AP23464

AP23464 is a potent adenosine 5'-triphosphate (ATP)-based inhibitor of Src and Abl kinases, displays antiproliferative activity against a human CML cell line and Bcr-Abl-transduced Ba/F3 cells (IC(50) = 14 nM. AP23464 ablates Bcr-Abl tyrosine phosphorylation, blocks cell cycle progression, and promotes apoptosis of Bcr-Abl-expressing cells. Biochemical assays with purified glutathione S transferase (GST)-Abl kinase domain confirmed that AP23464 directly inhibits Abl activity. Importantly, the lo...
T37505 MCTR1

MCTR1

Maresin conjugates in tissue regeneration 1 (MCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is then converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase. MCTR1 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR1 (50 ng/mouse, i.p.) prior to E. coli administration reduces neutrophil infiltration, shortens the inflam...

化合物

GSTO1-IN-1
Cat.No: T11505
Synonym:
Target: Glutathione Peroxidase, GST
Ethacrynic acid
Cat.No: T4564
Synonym: Edecrin,利尿酸,Etacrynic Acid,Hydromedin
Target: Others, Calcium Channel, NF-κB, GST
Ezatiostat
Cat.No: T5097
Synonym: TER199(free base),TLK199
Target: Apoptosis, Glutathione Peroxidase, GST
Ezatiostat hydrochloride
Cat.No: T22776
Synonym: TLK199 HCl,Ezatiostat盐酸盐,TER199
Target: Glutathione Peroxidase
S-Methylglutathione
Cat.No: T24807
Synonym: Glutathione S-methyl ester,Glutathione ester,S-Methyl glutathione
Target: Glyoxalase
Ezatiostat TFA
Cat.No: T5862
Synonym: TER199(free base),Ezatiostat TFA (free base),Ezatiostat,TLK199
Target: GST
NBDHEX
Cat.No: T12189
Synonym:
Target: Apoptosis, Glutathione Peroxidase, Autophagy
Oltipraz
Cat.No: T0153
Synonym: 吡噻硫酮,NSC 347901,RP 35972
Target: HIF/HIF Prolyl-Hydroxylase, HIV Protease, Reverse Transcriptase, Nrf2, HIF
Cysfluoretin
Cat.No: T23929
Synonym:
Target:
(S)-alpha-Fluoromethylhistidine 2 HCl
Cat.No: T26374
Synonym:
Target:
GSTO-IN-2
Cat.No: T11504
Synonym:
Target: Others
TLK117
Cat.No: T8424
Synonym: TER117
Target: Others
BITC-SG
Cat.No: T25160
Synonym:
Target:
Hexylglutathione
Cat.No: T27541
Synonym: NSC 131114,NSC-131114,NSC131114,S-Hexylglutathione
Target:
S-Octylglutathione
Cat.No: T81136
Synonym:
Target:
LAS17
Cat.No: T39906
Synonym: LAS17
Target:
PABA/NO
Cat.No: T68464
Synonym:
Target:
Cyclopropenone probe 1
Cat.No: T72328
Synonym:
Target:
GST-IN-1
Cat.No: T78800
Synonym:
Target:
Benastatin B
Cat.No: T70798
Synonym:
Target:
Benastatin C
Cat.No: T35979
Synonym:
Target:
PCTR3
Cat.No: T37302
Synonym:
Target:
PCTR2
Cat.No: T37301
Synonym:
Target:
canfosfamide hydrochloride
Cat.No: T67975
Synonym:
Target:
Canfosfamide
Cat.No: T75245
Synonym:
Target:
Benastatin A
Cat.No: T35978
Synonym:
Target:
Brostallicin HCl
Cat.No: T69978
Synonym:
Target:
MCTR2
Cat.No: T37506
Synonym: MCTR2
Target:
S-NEPC
Cat.No: T36074
Synonym:
Target:
A1-Phytoprostane-I
Cat.No: T36170
Synonym: A1-Phytoprostane-I
Target:
PCTR1
Cat.No: T37300
Synonym: PCTR1
Target:
Keap1-Nrf2-IN-9
Cat.No: T74600
Synonym:
Target:
MCTR3
Cat.No: T37507
Synonym: MCTR3
Target:
AP23464
Cat.No: T68581
Synonym:
Target:
MCTR1
Cat.No: T37505
Synonym: MCTR1
Target:
Cat. No. Product Name Target Signaling Pathways
T3S0012 coniferyl ferulate

P-gp; GST Membrane transporter/Ion channel; Neuroscience; oxidation-reduction
Coniferyl ferulate 是从川芎中提取的一种天然产物,是强效的谷胱甘肽 S-转移酶抑制剂,强抑制人胎盘型谷胱甘肽 S-转移酶,IC50为 0.3 μM。它还可逆转多药耐药性并下调 P-糖蛋白。
TN1078 Seneciphylline

千里光菲灵碱,千里光非灵

P450; GST Metabolism; oxidation-reduction
Seneciphylline 是一种有毒的吡咯烷核生物碱,存在于千里光植物中。它显著增加了环氧水合酶和谷胱甘肽-S-转移酶的特性,但导致细胞色素 P-450 和相关单加氧酶特性的抑制。
T7995 α-Angelica lactone

α-当归内酯,当归内酯,Alpha-Angelica Lactone

Others; GST Others; oxidation-reduction
α-Angelica lactone 是一种乙烯基亲核试剂,也是一种天然存在的抗癌剂。它可以得到手性的 δ-氨基 γ,γ-二取代丁烯醇内酯羰基衍生物,并在 γ-碳上表现出亲电子俘获。它通过选择性增强谷胱甘肽-S-硫转移酶 (GST) 和 UDP-葡糖苷转移酶 (UGT) 解毒酶发挥强大的化学保护作用。
T3S0541 Curzerene

莪术烯,莪术呋喃烯

Apoptosis; GST Apoptosis; oxidation-reduction
Curzerene, a sesquiterpene compound derived from the rhizome of Curculigo orchioides Gaertn, possesses potent anti-cancer properties. It is known to induce apoptosis in cells[1] and also suppress the expression of glutathione S-transferase A1 (GSTA1) mRNA and protein.
T5654 Musk ketone

Others Others
Musk ketone 可诱导癌细胞生长抑制和凋亡。它增加谷胱甘肽 S-转移酶的活性,因此可能被证明是有用的癌症化学保护剂。
T11680 Isoasatone A

P450 Metabolism
Isoasatone A 是一种具有抗虫作用的天然产物,分离自Heterotropa takaoiM。它作用于细胞色素 P450 单加氧酶和谷胱甘肽转移酶,产生抗S. litura 作用。
T3S0218 Thonningianin A

Apoptosis; Others Apoptosis; Others
Thonningianin A 是从非洲草药通宁宁的甲醇提取物中,分离得到的一种鞣花素,具有抗癌和抗氧化性,涉及自由基清除、抗超氧化物形成和金属螯合。
T6S0071 Fraxinellone

HIF/HIF Prolyl-Hydroxylase; STAT; PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Metabolism; Stem Cells
Fraxinellone 是从白鲜的根皮中分离出来的一种天然产物,是PD-L1抑制剂,可抑制HIF-1α蛋白质合成。它通过靶向 PD-L1,有用于癌症免疫的潜力。
TN2849 3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid

Antifection Microbiology/Virology
2-O-beta-d-Glucosyloxy-4-methoxybenzenepropanoic acid[3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid] exhibits glutathione S-transferase (GST) inhibitory and antifungal activities.
TN4345 Jacobine

Others Others
Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. It was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments.

天然产物

coniferyl ferulate
Cat.No: T3S0012
Synonym:
Target: P-gp, GST
Seneciphylline
Cat.No: TN1078
Synonym: 千里光菲灵碱,千里光非灵
Target: P450, GST
α-Angelica lactone
Cat.No: T7995
Synonym: α-当归内酯,当归内酯,Alpha-Angelica Lactone
Target: Others, GST
Curzerene
Cat.No: T3S0541
Synonym: 莪术烯,莪术呋喃烯
Target: Apoptosis, GST
Musk ketone
Cat.No: T5654
Synonym:
Target: Others
Isoasatone A
Cat.No: T11680
Synonym:
Target: P450
Thonningianin A
Cat.No: T3S0218
Synonym:
Target: Apoptosis, Others
Fraxinellone
Cat.No: T6S0071
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1
3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid
Cat.No: TN2849
Synonym:
Target: Antifection
Jacobine
Cat.No: TN4345
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-00539 GSTA1 Protein, Human, Recombinant (His)

glutathione S-transferas...

Human HEK293 Cells
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adeno...
TMPY-03450 GSTK1 Protein, Human, Recombinant

glutathione S-transferas...

Human E. coli
GSTK1 gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. Glutathione S-transferases (GSTs) are a family of enzymes that catalyze a variety of reactions in both eukaryotes and prokaryotes. They catalyze the conjugation of reduced glutathione with potentially toxic, xenobiotic substrates, thus aiding excretion from the body. GSTK1(glutathione S-transferase kappa 1) is localized to the peroxisome and catalyzes the...
TMPY-03338 GSTZ1 Protein, Human, Recombinant (His)

MAI,GSTZ1-1,glutathione S-tran

Human E. coli
GSTZ1 (Glutathione S-Transferase Zeta 1) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. GSTZ1 gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. GSTZ1 is a bifunctional protein that has minimal glutathione-conjugating activity with ethacrynic acid ...
TMPY-00027 GSTT2B Protein, Human, Recombinant (His)

GSTT2P,glutathione S-trans

Human HEK293 Cells
GSTT2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29 kDa and the accession number is P0CG29.
TMPY-01554 GSTM5 Protein, Human, Recombinant (His)

GSTM5-5,glutathione S-trans

Human E. coli
GSTM5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27.9 kDa and the accession number is AAH58881.1.
TMPY-02223 GSTM2 Protein, Human, Recombinant (His)

GSTM2-2,GTHMUS,glutathione S<...

Human E. coli
Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, si...
TMPJ-00499 GSTP1 Protein, Human, Recombinant

GSTP1,GST3,GST class...

Human E. coli
Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione ...
TMPJ-00690 PGDS Protein, Human, Recombinant

Glutathione-Requiring Prostaglandin D ...

Human E. coli
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydrop...
TMPY-02157 GST Protein, Schistosoma japonicum, Recombinant

Schistosoma japonicum Baculovirus Insect Cells
Genetic engineers have used glutathione S-transferase to create the GST gene fusion system. This system is used to purify and detect proteins of interest. In a GST gene fusion system, the GST sequence is incorporated into an expression vector alongside the gene sequence encoding the protein of interest. Induction of protein expression from the vector's promoter results in expression of a fusion protein: the protein of interest fused to the GST protein. This GST-fusion protein can then be purifie...
TMPY-01480 LTC4S Protein, Human, Recombinant (His)

LTC4S,MGC33147,leukotriene C4 synthas<...

Human Baculovirus Insect Cells
Leukotriene C4 synthase, also known as LTC4 synthase, Leukotriene-C(4) synthase, and LTC4S, is a multi-pass membrane protein that belongs to the MAPEG family. LTC4S is detected in the lung, platelets, and the myelogenous leukemia cell line KG-1 (at protein level). LTC4S activity is present in eosinophils, basophils, mast cells, certain phagocytic mononuclear cells, endothelial cells, vascular smooth muscle cells, and platelets. LTC4S is essential for the production of cysteinyl leukotrienes (Cys...

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GSTA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00539
Species: Human
Expression System: HEK293 Cells
GSTK1 Protein, Human, Recombinant
Cat.No: TMPY-03450
Species: Human
Expression System: E. coli
GSTZ1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03338
Species: Human
Expression System: E. coli
GSTT2B Protein, Human, Recombinant (His)
Cat.No: TMPY-00027
Species: Human
Expression System: HEK293 Cells
GSTM5 Protein, Human, Recombinant (His)
Cat.No: TMPY-01554
Species: Human
Expression System: E. coli
GSTM2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02223
Species: Human
Expression System: E. coli
GSTP1 Protein, Human, Recombinant
Cat.No: TMPJ-00499
Species: Human
Expression System: E. coli
PGDS Protein, Human, Recombinant
Cat.No: TMPJ-00690
Species: Human
Expression System: E. coli
GST Protein, Schistosoma japonicum, Recombinant
Cat.No: TMPY-02157
Species: Schistosoma japonicum
Expression System: Baculovirus Insect Cells
LTC4S Protein, Human, Recombinant (His)
Cat.No: TMPY-01480
Species: Human
Expression System: Baculovirus Insect Cells
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